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Table 4 Distribution of the EPIC hormone bother domain items before and after 6 and 12 months of androgen-deprivation therapy

From: Effects of a luteinizing hormone-releasing hormone agonist on cognitive, sexual, and hormonal functions in patients with prostate cancer: relationship with testicular and adrenal androgen levels

 

No such symptom

No problem

Very small problem

Small problem

Moderate problem

Big problem

Hot flashes*

 Pre

80.0%

6.7%

11.1%

2.2%

0.0%

0.0%

 6Mo

46.7%

11.1%

20.0%

8.9%

13.3%

0.0%

 12Mo

31.1%

15.6%

17.8%

20.0%

8.9%

6.7%

Breast tenderness/enlargement

 Pre

95.6%

2.2%

0.0%

0.0%

0.0%

2.2%

 6Mo

93.3%

4.4%

2.2%

0.0%

0.0%

0.0%

 12Mo

84.4%

8.9%

4.4%

2.2%

0.0%

0.0%

Loss of body hair

 Pre

91.1%

6.7%

0.0%

0.0%

2.2%

0.0%

 6Mo

86.7%

6.7%

6.7%

0.0%

0.0%

0.0%

 12Mo

66.7%

15.6%

8.9%

6.7%

2.2%

0.0%

Feeling depressed

 Pre

66.7%

8.9%

17.8%

4.4%

2.2%

0.0%

 6Mo

62.2%

17.8%

8.9%

6.7%

4.4%

0.0%

 12Mo

66.7%

17.8%

8.9%

6.7%

0.0%

0.0%

Lack of energy

 Pre

57.8%

11.1%

15.6%

15.6%

0.0%

0.0%

 6Mo

55.6%

17.8%

13.3%

8.9%

4.4%

0.0%

 12Mo

46.7%

15.6%

28.9%

4.4%

2.2%

2.2%

Change in body weight

 Pre

84.4%

11.1%

4.4%

0.0%

0.0%

0.0%

 6Mo

57.8%

17.8%

15.6%

4.4%

2.2%

2.2%

 12Mo

62.2%

20.0%

11.1%

4.4%

0.0%

2.2%

  1. *p < 0.001.