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Table 3 CFTR RNA sequencing and GeneChip (Affymetrix) data analysis and SLC9A-family RNA sequencing data. FC; the log-fold changes, FDR; false discovery rate, RPKM; median expression values expressed in reads per kilobase per million, before and after GnRHa treatment [15, 21, 22]

From: A novel role for CFTR interaction with LH and FGF in azoospermia and epididymal maldevelopment caused by cryptorchidism

Gene

HIR/LIR (RPKM)

log2FC / FDR

−/+ GnRHa treatment (RPKM)

log2FC / FDR

Affymetrix probeset identifier (highest variance probe set per gene)

Descended / undescended (HIR + LIR, median log2 signal)

log2FC / FDR

CFTR

0.24/0.79

−1.50/0.001

0.29/1.54

1.35/0.002

205043_at

3.39/3.50

n.s.

SLC9A3R1

0.69/2.07

−1.43/5.77E-05

n.s.

n.s.

   

SLC9A2

n.s

n.s.

0.13/1.00

2.18/1.69E-05

   

SLC9A4

n.s

n.s.

0.13/0.42

2.12/0.0001

   

SLC9A9-AS1

n.s

n.s.

0.32/2.39

2.77/0.001

   
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Basic and Clinical Andrology

ISSN: 2051-4190