Combination of pregabalin and Amitriptyline in management of chronic idiopathic pain following penile prosthesis implantation: a pilot study

Table 3 Difference between pain outcomes [immediate, 10 days, 30 days and 100 days postoperatively] in included cases

	Immediate Postop	10 Days Postop	30 Days Postop	100 Days Postop	P
Duration of Pain Episode (min)
None	0 (0%)	3 (33.3%)	3 (33.3%)	4 (44.4%)	0.007^a S
< 15 min	0 (0%)	5 (55.6%)	5 (55.6%)	4 (44.4%)
≥ 15 min	9 (100%)	1 (11.1%)	1 (11.1%)	1 (11.1%)
Frequency of Pain Episodes
Range	2 – 7	0 – 5	0 – 4	0 – 4	< 0.001^b S
Median (IQR)	4 (3 – 5)	1 (0 – 3)	1 (0 – 3)	1 (0 – 2)	< 0.001^b S
Location of Pain
Glans	8 (88.9%)	4 (44.4%)	4 (44.4%)	3 (33.3%)	0.008 (S)^a
Shaft	6 (66.7%)	4 (44.4%)	4 (44.4%)	2 (22.2%)	0.046 (S)^a
Scrotum	2 (22.2%)	0 (0%)	0 (0%)	0 (0%)	0.112 (NS)^a
Character of Pain
Sharp	7 (77.8%)	1 (11.1%)	4 (44.4%)	1 (11.1%)	0.003 (S)^a
Aching	2 (22.2%)	5 (55.6%)	2 (22.2%)	4 (44.4%)	0.277 (NS)^a
Pain Aggravated by Touch
Yes	7 (77.8%)	3 (33.3%)	3 (33.3%)	2 (22.2%)	0.008^a S
No	2 (22.2%)	6 (66.7%)	6 (66.7%)	7 (77.8%)	0.008^a S
VAS for Pain
Range	4 – 7	0 – 3	0 – 2	0 – 1	< 0.001^b S
Median (IQR)	5 (5 – 7)	1 (0 – 2)	1 (0 – 1)	1 (0 – 1)	< 0.001^b S
QoL
Satisfied	1 (11.1%)	8 (88.9%)	9 (100%)	9 (100%)	< 0.001^a S
Unsatisfied	8 (88.9%)	1 (11.1%	0 (0%)	0 (0%)	< 0.001^a S

SD standard deviation, IQR interquartile range, VAS visual analogue scale, QoL quality of Life, S significant, NS non-significant
Data presented as range, mean ± SD; range, median (IQR); or frequency (percentage)
^aAnalysis using Cochran’s Q-Test
^bAnalysis using Friedman’s Two-Way Test

ISSN: 2051-4190