Genetic diagnosis and outcomes of intracytoplasmic sperm injection in South Chinese patients with congenital bilateral aplasia of the vas deferens

Table 3 Laboratory and clinical outcomes of OA couples in ICSI cycles

	CFTR Mutation	no-CBAVD-OA	P
n	30	112
Male age (years)	32(30 ~ 33)	33(30 ~ 36)	0.145
Female age (years)	29(27.25 ~ 33)	31(27.75 ~ 35)	0.171
Fertilization rate	77.10% (293/380)	76.76% (1126/1467)	0.94
2PN rate	79.52% (233/293)	86.15% (970/1126)	0.0065
Average number of available embryos	5(3 ~ 6.75)	4(2 ~ 7)	0.212
Clinical pregnancy rate/fresh ET (n)	60% (18/30)	52.68% (59/112)	0.475
Miscarriage Rate	16.7% (3/18)	11.8% (7/59)	0.897
Live Birth Rate	50% (15/30)	46.43% (52/112)	0.728

This table compares the laboratory and clinical outcomes of couples with Congenital Bilateral Aplasia of the Vas Deferens (CBAVD) and those with other forms of obstructive azoospermia (No-CBAVD-OA) undergoing ICSI cycles
Continuous variables were presented as medians (first quartile-third quartile) and compared using the Mann–Whitney U rank-sum test
Categorical variables were presented as % (n/N) and compared using the chi-square test
CFTR Cystic fibrosis transmembrane conductance regulator, 2PN rate 2 Pronuclei rate, CBAVD Congenital bilateral absence of the vas deferens, ICSI Intracytoplasmic Sperm Injection, OA Obstructive azoospermia
P value < 0.05 was considered statistically significant

ISSN: 2051-4190