Genetic diagnosis and outcomes of intracytoplasmic sperm injection in South Chinese patients with congenital bilateral aplasia of the vas deferens

Table 4 Laboratory and Clinical Outcomes of CBAVD Couples with and without CFTR Mutation in ICSI Cycles

Characteristic	CFTR Mutation	no- CFTR Mutation	P
n	30	11
Male age (years)	32(30 ~ 33)	31(27 ~ 33)	0.145
Female age (years)	29(27.2 ~ 33)	30(28 ~ 34)	0.171
Fertilization rate	77.1% (293/380)	72.4% (92/127)	0.28
2PN rate	79.5% (233/293)	77.2% (71/92)	0.66
Average number of available embryos	5(3 ~ 6.75)	3(1.5 ~ 6.5)	0.18
Clinical pregnancy rate/fresh ET (n)	60% (18/30)	63.6% (7/11)	1
Miscarriage Rate	16.7% (3/18)	14.2% (1/7)	1
Live Birth Rate	50% (15/30)	54.5% (52/112)	1

This table compares the laboratory and clinical outcomes of couples with CBAVD undergoing ICSI cycles, divided into groups based on the presence or absence of CFTR mutations
Categorical variables were presented as % (n/N) and compared using the Fisher's precision probability test
Continuous variables were presented as medians (first quartile-third quartile) and compared using the Mann–Whitney U rank-sum test
CFTR Cystic fibrosis transmembrane conductance regulator, 2PN rate 2 Pronuclei rate
P value < 0.05 was considered statistically significant

ISSN: 2051-4190