Is testicular microlithiasis associated with decreased semen parameters? a systematic review

Table 6 Comparison of average testicular volume in 3 studies that compared men with classic testicular microlithiasis (≥ 5 microcalcifications per sonographic image) to those with limited testicular microlithiasis (< 5 microcalcifications per sonographic image)

Authors and reference number	Year	Number in Sample		Testicular volume
Authors and reference number	Year	CTM	LTM	Volume compared to LTM	Statistically significant difference?
*Infertile Population:*
D’Andrea et al. [9]	2021	46	47	↓	✓
Rassam et al. [32]	2020	53	134	↓	✗
*Population not specified:*
Xu et al. [35]	2014	97	62	↓	✓

Summary table of the included studies that compared testicular volume in men with classic testicular microlithiasis compared to men with limited testicular microlithiasis. The table indicates the direction of the difference in the classic testicular microlithiasis group compared to the limited testicular microlithiasis group and if the difference was statistically significant. CTM classic testicular microlithiasis, LTM limited testicular microlithiasis, ✓: Yes (in response to the question in the respective column), ✗: No (in response to the question in the respective column), ↓: decrease, ↑: increase. Blank spaces indicate that there was insufficient data available to answer the question

ISSN: 2051-4190